Jason Weick

Ph.D. 2005

Thesis Title:

Activity-Dependent Synaptic Plasticity: Cooperative Signaling Between Synapse and Nucleus

Current Position:

Assistant Professor
Department of Neurosciences
University of New Mexico

Major Advisor(s):

Paul Mermelstein, Ph.D.

Selected Publications:

  • Liu, Y-L., Weick, J.P., Liu, H-S., Krencik, R., Zhang S.C. Basal forebrain cholinergic neurons reverse learning and memory deficits in mouse models of aging. (in revision)
  • Weick, J.P., Held, D.L., Bonadurer, G., Doers, M.E., Clark, A., Maguire, C., Knackert, J.A., Molinarolo, K., Zhang X., Zhang, S.C., and Bhattacharyya, A. Cellular and molecular defects in human Down syndrome induced pluripotent stem cells (iPSCs) and their neuronal derivatives. (in revision)
  • Weick, J.P., Liu, Y., and Zhang, S.C. Human embryonic stem cell-derived neurons adopt and regulate the activity of an established neural network. Proc Natl Acad Sci. 2011 Dec 13;108(50):20189-94.
  • Krencik, R., Weick, J.P., Liu, Y., Zhang, Z.J., and Zhang, S.C. Specification of transplantable astroglial subtypes from human pluripotent stem cells. Nature Biotechnology 2011 May 22;29 (6):528–534.
  • Weick, J.P., Johnson, M.A., Skroch, S.P., Williams, J.C., Deisseroth K., and Zhang, S.C. Functional control of transplantable human ESC-derived neurons via optogenetic targeting. Stem Cells 2010 Nov 28(11):2008-16.
  • Hu B.Y., Weick, J.P., Yu, J., Thomson, J.A., and Zhang, S.C. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency.  Proc. Natl. Acad. Sci. 2010 Mar 2;107(9):4335-40. 
  • Weick, J.P., Johnson, M.A., and Zhang, S.C. Developmental regulation of human embryonic stem cell-derived neurons by calcium entry via transient receptor potential (Trp) Channels. Stem Cells 2009 Dec 27(12):2906-2916.
  • Lavaute, T.M., Yoo, Y.D., Pankratz, M.T., Weick, J.P., Gerstner J.D., and Zhang, S.C. Regulation of neural specification from human embryonic stem cells by BMP and FGF. Stem Cells 2009 Apr 23; 27(8):1741-1749.
  • Groth, R.D.*, Weick, J.P.*, Bradley, K.T., Luoma, J.I., Aravmudan, B., Klug, J.R., Thomas, M.J., and Mermelstein, P.G. D1 Dopamine Dopamine Receptor Activation of NFAT-mediated Striatal Gene Expression. Eur. J. Neurosci. 2008 Jan; 27(1):31-42. *Denotes equal contribution
  • Johnson, M.A., Weick, J.P., Pearce, R.A., and Zhang, S.C. Functional Neural Development from Human Embryonic Stem Cells: Accelerated Synaptic Activity via Astrocyte Co-Culture. J. Neurosci. 2007 Mar 21; 27(12):3069-77.
Jason Weick