Our Brain Plasticity Lab is a clinical research laboratory which studies the neuropathophysiology of motor impairment and strives to develop novel rehabilitation interventions for neurologic disorders, such as stroke and dystonia. We use neuroimaging (functional magnetic resonance imaging and diffusion tensor imaging) and non-invasive neuromodulation (transcranial magnetic stimulation and transcranial direct current stimulation) tools to help discover the mechanism of recovery from a neurologic disorder, improve diagnosis, and optimize recovery strategies. Dr. Kimberley was awarded the esteemed University of Minnesota Outstanding Advisor award for her dedication to her trainees.
(For a comprehensive list of recent publications, refer to PubMed, a service provided by the National Library of Medicine.)
Chen M, Deng H, Schmidt RL, Kimberley TJ. Low-Frequency Repetitive Transcranial Magnetic Stimulation Targeted to Premotor Cortex Followed by Primary Motor Cortex Modulates Excitability Differently Than Premotor Cortex or Primary Motor Cortex Stimulation Alone. Neuromodulation. 2015 Aug 26.
Kimberley TJ, Schmidt RL, Chen M, Dykstra DD, Buetefisch CM. Mixed effectiveness of rTMS and retraining in the treatment of focal hand dystonia. Front Hum Neurosci. 2015 Jul 9;9:385.
Cassidy JM, Chu H, Anderson DC, Krach LE, Snow L, Kimberley TJ, Carey JR. A Comparison of Primed Low-frequency Repetitive Transcranial Magnetic Stimulation Treatments in Chronic Stroke. Brain Stimul. 2015 Jun 22.
Samargia S, Schmidt R, Kimberley TJ. Cortical Silent Period Reveals Differences Between Adductor Spasmodic Dysphonia and Muscle Tension Dysphonia. Neurorehabil Neural Repair. 2015 Jun 18.
Kimberley TJ, Borich MR, Schmidt RL, Carey JR, Gillick B. Focal hand dystonia: individualized intervention with repeated application of repetitive transcranial magnetic stimulation. Arch Phys Med Rehabil. 2015 Apr;96(4 Suppl):S122-8.
Dawson J, Pierce D, Dixit A, Kimberley TJ, Tarver RM, Hilmi O, McLean J, Forbes K, Kilgard M, Rennaker R, Cramer S, Walters M, Engineer N. Safety, Feasibility and Efficacy of Vagus Nerve Stimulation Paired with Arm Rehabilitation Following Ischaemic Stroke. Stroke, in press
Bradnam LV, Frasca J, Kimberley TJ. Direct current stimulation of primary motor cortex and cerebellum and botulinum toxin a injections in a person with cervical dystonia. Brain Stimul. 2014 Nov-Dec;7(6):909-11.
Samargia S, Schmidt R, Kimberley TJ. Shortened cortical silent period in adductor spasmodic dysphonia: evidence for widespread cortical excitability. Neurosci Lett. 2014 Feb 7;560:12-5.
Gillick BT, Krach LE, Feyma T, Rich TL, Moberg K, Menk J, Cassidy J, Kimberley T, Carey JR. Safety of primed repetitive transcranial magnetic stimulation and modified constraint-induced movement therapy in a randomized controlled trial in pediatric hemiparesis. Archives of physical medicine and rehabilitation. 2015: S104-S113
Deng H, Kimberley TJ, Durfee WK, Dressler BL, Steil C, Carey JR. Combined Statistical Analysis Method Assessing Fast vs. Slow Movement Training in a Single-Case with Cerebellar Stroke. Physical Therapy, 2013 May;93(5):649-660.
Kimberley TJ, Borich MR, Arora S, Siebner HR. Multiple sessions of low-frequency repetitive transcranial magnetic stimulation in focal hand dystonia: clinical and physiological effects. Restorative Neurology and Neuroscience, 2013: 31(5);533-542.
Kimberley TJ & Pickett KA. Differential activation in the primary motor cortex during individual digit movement in focal hand dystonia vs. healthy. Restorative Neurology and Neuroscience,30: 247-254, 2012
Borich MR, Kimberley TJ. Using actigraphy and transcranial magnetic stimulation to assess the relationship between sleep and visuomotor skill learning. Restorative Neurology and Neuroscience. 30:81-90, 2012
Olman CA, Pickett KA, Schallmo MP, Kimberley TJ. Selective BOLD responses to individual finger movements measured with fMRI at 3T. Human Brain Mapping, 33(7):1594-1606, 2012
Borich MR & Kimberley TJ. Both sleep and wakefulness support consolidation of continuous, goal-directed, visuomotor skill. Experimental Brain Research, 214(4):619-630, 2011